Synergistic Effect in Hybrid Plasmonic Conjugates for Photothermal Applications.

ABSTRACT: Photothermal conversion efficiency (η) plays a crucial role in selecting suitable gold nanoparticles for photothermal therapeutic applications. The photothermal efficiency depends on the material used for the nanoparticles as well as their various parameters, such as size and shape. By maximizing the light-to-heat conversion efficiency (η), one can reduce the concentration of nanoparticle drugs for photothermal cancer treatment and apply lower laser power to irradiate the tumor. In our study, we explored a new hybrid plasmonic conjugate for theranostic (therapy + diagnostic) applications. We conjugated PEG-functionalized 20 nm gold nanospheres with cyanine IR dyes via a PEG linker. The resulting conjugates exhibited significantly enhanced photothermal properties compared with bare nanopart

SUBMITTER: Savchuk V 

PROVIDER: S-EPMC11618431 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature