Clinical and Genetic Findings in Patients With Palmoplantar Keratoderma.

ABSTRACT:

Importance

Palmoplantar keratoderma poses diagnostic challenges due to its clinical and genetic heterogeneity, and knowledge on the value of systematic genetic testing on clinically well-described patient cohorts is sparse.

Objective

To improve knowledge of the clinical and genetic spectrum of patients with palmoplantar keratoderma.

Design, setting, and participants

This cohort study prospectively recruited patients and affected family members with palmoplantar keratoderma between September 1, 2016, and December 31, 2022. Patients were recruited from private practitioners in dermatology and dermatology departments in Denmark. Study participants were patients 18 years or older either newly diagnosed with palmoplantar keratoderma or being followed up for the disease at

SUBMITTER: Gram SB 

PROVIDER: S-EPMC11618570 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature