Effects of Pancreatic Fistula After Minimally Invasive and Open Pancreatoduodenectomy.

ABSTRACT:

Importance

Postoperative pancreatic fistulas (POPF) are the biggest contributor to surgical morbidity and mortality after pancreatoduodenectomy. The impact of POPF could be influenced by the surgical approach.

Objective

To assess the clinical impact of POPF in patients undergoing minimally invasive pancreatoduodenectomy (MIPD) and open pancreatoduodenectomy (OPD).

Design, setting, and participants

This cohort study was conducted from 2007 to 2020 in 36 referral centers in Europe, South America, and Asia. Participants were patients with POPF (grade B/C as defined by the International Study Group of Pancreatic Surgery [ISGPS]) after MIPD and OPD (MIPD-POPF, OPD-POPF). Propensity score matching was performed in a 1:1 ratio based on the variables age (continuous), sex, bo

SUBMITTER: Bruna CL 

PROVIDER: S-EPMC11618579 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature