Diffusion Coefficients of Coated Plasmonic Nanoparticles in Viscous Environment.

ABSTRACT: The Stokes-Einstein relationship (SER) is not valid anymore in polymeric solutions for nanoparticles. It is thus important to characterize their diffusion properties to get a finer understanding of their behavior and to better tune their attributes for biomedical applications. The diffusion of gold and silver nanoparticles with citrate, hyaluronic acid, methyl-polyethylene glycol, and antibody-polyethylene glycol coatings is studied in hyaluronic-based viscous solutions. The diffusion coefficient D is estimated from the Brownian motion thanks to a cost-effective side-illumination device. It is determined that the nanoparticles (hydrodynamic radius r_h: 30-135 nm) diffuse up to 4-5 times faster than expected using the SER with a macroscopic viscosity from 1 to 30 mPa·s. It is show

SUBMITTER: Largilliere I 

PROVIDER: S-EPMC11618706 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature