<i>Helicobacter pylori</i> Seroprevalence in Rheumatoid Arthritis Patients with Interstitial Lung Disease.

ABSTRACT:

Background

Rheumatoid arthritis (RA) is complicated with interstitial lung disease (ILD). Gastroesophageal reflux disease is prevented by Helicobacter pylori infection and is a predisposing factor for idiopathic pulmonary fibrosis. However, the prevalence of H. pylori infection in RA patients with ILD has not been sufficiently investigated.

Objective

In this study, we analyzed anti-H. pylori antibodies in RA patients with ILD.

Design

Case-control observational study.

Methods

Anti-H. pylori antibodies were analyzed in the sera of RA patients using a commercially available enzyme-linked immunosorbent assay kit.

Results

The positivity of anti-H. pylori antibodies in RA with ILD (n = 30 [18.0%], P = .0227), us

SUBMITTER: Oka S 

PROVIDER: S-EPMC11618895 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature