Tailored culture strategies to promote antimicrobial secondary metabolite production in Diaporthe caliensis: a metabolomic approach.

ABSTRACT:

Background

In the search for new antimicrobial secondary metabolites of fungi, optimizing culture conditions remains a critical challenge, as standard laboratory approaches often result in low yields. While non-selective methods, such as modifying culture media, have been effective in expanding the chemical diversity of fungal metabolites, they have not yet established a direct link to key process parameters crucial for further optimization. This study investigates the capacity of Diaporthe caliensis as a biofactory for biologically active secondary metabolites, employing tailored culture media to explore the relationship between chemical diversity and critical process variables.

Results

The metabolomic profiles, antibacterial activities, and production yields of the extract

SUBMITTER: Hoyos LV 

PROVIDER: S-EPMC11619134 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature