Broad-spectrum antimicrobial activities of a food fermentate of Aspergillus oryzae.

ABSTRACT: Amid persistent concerns over microbial foodborne illnesses and escalating antibiotic resistance, we introduce "NP," a novel and effective broad-spectrum natural antimicrobial product derived from the filtered culture broth of Aspergillus oryzae grown in a food-grade liquid medium. NP demonstrates potent bactericidal activity against a range of food-borne and ESKPAE pathogens, including Staphylococcus aureus (including eight distinct drug-resistant methicillin-resistant Staphylococcus aureus strains), Listeria monocytogenes, Salmonella typhimurium, Klebsiella pneumonia, Pseudomonas aeruginosa, and Escherichia coli (including O157:H7) with minimal inhibitory strength ranging from 25% to 100%. In addition, NP

SUBMITTER: Choi D 

PROVIDER: S-EPMC11619415 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature