Associations between longitudinal fluoride intakes from birth to age 23 and multi-row detector computed tomography bone densitometry outcomes at age 23.

ABSTRACT:

Objectives

To assess the relationships between longitudinal fluoride intakes and bone densitometry outcomes in young adults.

Methods

Data were analyzed from the Iowa Fluoride Study and Iowa Bone Development Study, which followed 1,882 infants from birth in 1992. Daily fluoride intakes were assessed using detailed questionnaires sent every 1.5-6 months, and multi-row detector computed tomography (MDCT) scans of distal tibia were obtained from 330 participants aged 23 years. Sex-specific bivariate and multivariable associations with MDCT outcomes were examined using linear regression. Because of the multiple statistical analyses being conducted, p-values < 0.01 were considered statistically significant.

Results

In fully adjusted analyses, no statistically significant (p

SUBMITTER: Bhatia GK 

PROVIDER: S-EPMC11619560 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature