Genomic assessment of targets implicated in Rhipicephalus microplus acaricide resistance.

ABSTRACT: Globally, the prevalence of Rhipicephalus microplus resistance to various acaricides has increased, and there is a need for the identification of molecular markers that can predict phenotypic resistance. These markers could serve as alternatives to the larval packet test (LPT), enabling rapid and accurate monitoring of resistance in these ticks against multiple acaricides. However, many of the historically identified markers are present in isolates from specific countries and their role in acaricide resistance remains unclear. This study aimed to assess these mutations by sequencing genomic regions encoding proteins historically associated with acaricide target site insensitivity and increased acaricide detoxification and comparing resistant and susceptible isolates from eight different co

SUBMITTER: Meiring C 

PROVIDER: S-EPMC11620669 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature