Neuroimaging markers and disability scales in multiple sclerosis: A systematic review and meta-analysis.

ABSTRACT:

Background

Multiple sclerosis (MS) is a central nervous system disorder marked by progressive neurological impairments. Magnetic resonance imaging (MRI) parameters are key paraclinical measures that play a crucial role in the diagnosis, prognosis, and monitoring of MS-related disability. This study aims to analyze and summarize the existing literature on the correlation between MRI parameters and disability in people with MS (pwMS).

Methods

The PubMed/MEDLINE, Embase, Scopus, and Web of Science databases were searched from inception to July 19, 2024, and a meta-analysis was carried out using R software version 4.4.0 and the random effects model used to determine the pooled correlation coefficient, with its 95% confidence interval (CI), between MRI measurements and disability

SUBMITTER: Mirmosayyeb O 

PROVIDER: S-EPMC11620670 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature