Lipid accumulation product and gallstone risk in US adults: A cross-sectional analysis of NHANES 2017-2020 data.

ABSTRACT:

Background

Abdominal obesity and insulin resistance are key risk factors for gallstones. The Lipid Accumulation Product (LAP), which combines waist circumference and triglyceride levels, may be a superior marker for visceral fat accumulation. However, its association with gallstone risk is unclear.

Methods

Data from 3294 participants in the National Health and Nutrition Examination Survey (NHANES) 2017-2020 cycle were analyzed. Weighted logistic regression, subgroup analyses, and restricted cubic spline (RCS) analysis explored the relationship between LAP and gallstone risk. ROC analysis, along with Random Forest and CatBoost models, compared the predictive abilities of LAP with BMI.

Results

Weighted logistic regression analysis showed that each unit increase in Ln-LA

SUBMITTER: Li X 

PROVIDER: S-EPMC11620675 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature