Combination of triple chemotherapy and sequential re-irradiation as salvage for recurrent treatment-refractory hemangiopericytoma of extraspinal dura: a case report.

ABSTRACT:

Introduction

Hemangiopericytoma (HPC) in the central nervous system (CNS) is rare. Our report aims to present an HPC case with multiple surgeries at the lumbar spine, and demonstrates an effective treatment as salvage.

Case report

In this report, we present the case of a young girl with recurrent meningeal invasion of lumbar spinal HPC. The patient underwent multiple surgeries to remove the tumors, and adjuvant radiotherapy was administered after the initial resection. And it presented a pathological anaplastic transformation with subsequent accelerated recurrence. A combination therapy approach involving triple chemotherapy and sequential re-irradiation was found to be effective as salvage treatment at the third recurrence.

Conclusions

Surgical resection remains the

SUBMITTER: Wang M 

PROVIDER: S-EPMC11621096 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature