Extracellular vesicles of Janthinobacterium lividum as violacein carriers in melanoma cell treatment.

ABSTRACT: Violacein is a natural indole-derived purple pigment of microbial origin that has attracted attention for its remarkable biological properties. Due to its poor solubility in aqueous media, most studies of this pigment use extracts of the compound obtained with common solvents. Violacein is also transported in bacterial extracellular vesicles (EVs) and transferred via this type of carrier remains stable in an aqueous environment. This paper is the first to present an in-depth study of Janthinobacterium lividum EVs as violacein carriers. J. lividum EVs were studied for their contribution to violacein translocation, size, morphology and protein composition. The production of violacein encapsulated in EVs was more efficient than the intracellular production of this compound. The average size o

SUBMITTER: Kowalska P 

PROVIDER: S-EPMC11621134 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature