Predicting future fallers in Parkinson's disease using kinematic data over a period of 5 years.

ABSTRACT: Parkinson's disease (PD) increases fall risk, leading to injuries and reduced quality of life. Accurate fall risk assessment is crucial for effective care planning. Traditional assessments are subjective and time-consuming, while recent assessment methods based on wearable sensors have been limited to 1-year follow-ups. This study investigated whether a short sensor-based assessment could predict falls over up to 5 years. Data from 104 people with PD without prior falls were collected using six wearable sensors during a 2-min walk and a 30-s postural sway task. Five machine learning classifiers analysed the data. The Random Forest classifier performed best, achieving 78% accuracy (AUC = 0.85) at 60 months. Most models showed excellent performance at 24 months (AUC > 0.90, accuracy 84-92%).

SUBMITTER: Sotirakis C 

PROVIDER: S-EPMC11621420 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature