Dynamic [^99mTc]Tc-mebrofenin SPECT/CT in preoperative planning of liver resection: a prospective study.

ABSTRACT:

Background

At least 20% of the future liver remnant must function properly after liver tumor resection to avoid post-hepatectomy liver failure (PHLF). [^99mTc]Tc-mebrofenin scintigraphy and SPECT are unique noninvasive, quantitative methods for evaluating liver function via hepatocellular bilirubin clearance.

Aim

To evaluate the value of dynamic [^99mTc]Tc-mebrofenin SPECT/CT parameters for predicting clinically relevant PHLF according to the ISGLS criteria.

Methods

Thirty-five patients underwent dynamic [^99mTc]Tc-mebrofenin SPECT/CT imaging to determine the FLR volumetric rate, functional volume rate, total liver filtration and FLR filtration. On the same day, two-dimensional ultrasound shear wave elastography (2D-SWE) was used to asses

SUBMITTER: Bakos A 

PROVIDER: S-EPMC11621425 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature