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ABSTRACT: Background
Assessments of the efficacy of interventions to improve child growth are often based on differences in mean height-for-age z-scores (HAZ) and stunting (HAZ<-2) in randomized controlled trials (RCTs). However, this approach does not account for children's starting skeletal age and does not enable assessment of the extent to which interventions optimized linear growth.Objectives
The objectives of this study were to develop and apply a new method using height-age to express linear growth effects in RCTs.Methods
Longitudinal individual participant data (IPD) from a Bangladeshi trial cohort were used to compare height-age estimates derived from individual-level heights, mean raw height, or mean HAZ. Then, using mean height-age as a proxy for skeletal ag
SUBMITTER: Watson KM
PROVIDER: S-EPMC11621485 | biostudies-literature | 2024 Dec
REPOSITORIES: biostudies-literature