Creatine kinase-MB elevation in patients with acute aortic dissection predict worse in-hospital outcomes.

ABSTRACT:

Background

The aim of this study was to evaluate the association between baseline creatine kinase-myocardial band (CK-MB) and the risk of in-hospital all-cause mortality in acute type A and type B aortic dissection (AD) patients, and to explore the predictive value of CK-MB.

Methods

A single-center retrospective analysis was performed on 552 acute AD (type A 329 patients, type B 223 patients). Outcomes were the incidence of in-hospital all-cause mortality. Kaplan-Meier curve was used to compare the all-cause death risk in two groups (normal CK-MB group and elevated CK-MB group). The Cox regression model and restricted cubic splines (RCS) were conducted to assess the relationship between CK-MB and outcomes. Stratified analysis was performed based on gender, age (<50 years or 

SUBMITTER: Xin Y 

PROVIDER: S-EPMC11621597 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature