The role of Mediterranean diet in cancer incidence and mortality in the older adults.

ABSTRACT: The magnitude of benefit of Mediterranean diet in cancer prevention and mortality in older adults is still unclear, therefore we conducted a systematic review and meta-analysis. Outcomes considered were cancer incidence and cancer mortality. In studies evaluating cancer incidence as a time-to-event endpoint and adherence as quantiles, HR was 0.885 (95% CI 0.773-1.013, I² = 44%). Including ORs, exploratory pooled effect size was 0.876 (0.794-0.966, I² = 34%), consistently with results of studies evaluating ORs for adherence as one-point increase (OR 0.744, 0.570-0.972, I² = 90%). No clear benefit was observed on cancer mortality, with pooled HR of 0.935 (0.800-1.093, I² = 0%). Significant differences were observed for ORs according to cancer type

SUBMITTER: Giordano G 

PROVIDER: S-EPMC11621705 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature