Optimal lead time for treatment of infantile epileptic spasms syndrome-a secondary data analysis.

ABSTRACT:

Background

Infantile epileptic spasms syndrome (IESS) is a common epileptic syndrome in infancy. Current first-line treatments include adrenocorticotropic hormone (ACTH), corticosteroids and vigabatrin, with early control of epileptic spasms potentially benefiting long-term outcomes, such as improved psychomotor development. Early treatment, which means the prompt use of first-line treatments, is crucial for achieving an initial response in IESS. However, to date, no clear definition of the specific timeframe that constitutes early treatment has been identified. The objective of this study is to perform a secondary analysis of our previously published IESS cohort data to determine a suitable lead time.

Methods

An analysis was conducted using a cohort of 263 children with IES

SUBMITTER: Ge W 

PROVIDER: S-EPMC11621889 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature