The growth and development of children with β-thalassemia major one year after allogeneic hematopoietic stem cell transplantation.

ABSTRACT:

Background

Allogeneic hematopoietic stem cell transplantation (allo-HSCT) has proven to be an effective curative intervention for children with β-thalassemia major (β-TM). They are susceptible to growth disorders due various factors. The primary objective of this study was to investigate the growth and development of children with β-TM both before and after undergoing allo-HSCT during a one-year follow-up period.

Methods

According to the international reference standards for child growth established by the World Health Organization in 2006, participants were divided into two groups based on their Z scores: weight-for-age Z scores (WAZ), height-for-age Z scores (HAZ), and body mass index-for-age Z scores (BAZ) before allo-HSCT. The first group included children with normal nu

SUBMITTER: Luo H 

PROVIDER: S-EPMC11621892 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature