Cerebrospinal fluid red blood cells and total protein are associated with clinical outcome in spontaneous subarachnoid hemorrhage.

ABSTRACT:

Background and purpose

Prognostication in patients with spontaneous subarachnoid hemorrhage (SAH) can be challenging. The aim of this study was to assess whether cerebrospinal fluid (CSF) red blood cell (RBC) count and total protein (TP) concentration are associated with SAH prognosis.

Methods

Patients with SAH treated at the neurological intensive care unit (ICU) in Innsbruck were included in this real-world, observational study. Longitudinal CSF samples were collected as part of routine diagnostics. RBC count and CSF TP at the time of admission (RBC_first, TP_first), in Week 1 (RBC_Days1-7, TP_Days1-7), Week 2 (RBC_Days8-14, TP_Days8-14), and Week 3 or thereafter (RBC_Day>14, TP_Day>14), the hi

SUBMITTER: Berek K 

PROVIDER: S-EPMC11622267 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature