Explore the Staging of Cerebral Venous Thrombosis Through Fibrinolytic Indicators.

ABSTRACT:

Background

The stage of cerebral venous thrombosis (CVT) is crucial to guide treatment decisions. This study aims to examine changes in fibrinolytic indicators throughout CVT onset and validate a predictive model using admission fibrinolytic indicators to estimate the CVT stage.

Methods

Retrospective analysis was conducted on data from 292 CVT patients. We utilized linear regression, time series, and univariate ANOVA analyses to explore characteristics of change in fibrinolytic indicators with CVT duration and identified time point at which fibrinolysis indexes showed significant changes as the time point for acute and chronic stages of CVT. A nomogram was employed to construct a prediction model using a training set, which was then evaluated for discrimination, calibration,

SUBMITTER: Lan D 

PROVIDER: S-EPMC11622301 | biostudies-literature | 2024 Jan-Dec

REPOSITORIES: biostudies-literature