Zinc supplementation for acute and persistent watery diarrhoea in children: A systematic review and meta-analysis.

ABSTRACT:

Background

Zinc is a micronutrient that plays a role in immune system strengthening and regulation of intestinal epithelial cells, and can reduce the duration and severity of diarrhoea. We conducted a systematic review of randomised controlled trials (RCTs) to assess the effectiveness of zinc compared to no zinc for the management of acute and persistent diarrhoea in children.

Methods

We searched PubMed, the Cochrane Library, Scopus, CINAHL, ClinicalTrials.gov, and World Health Organization (WHO) International Clinical Trials Registry Platform from inception until 31 July 2023 for studies published from year 2000 onwards that assessed the use of zinc in the management of acute and persistent diarrhoea in children aged less than 10 years. We conducted the meta-analysis in Coc

SUBMITTER: Ali AA 

PROVIDER: S-EPMC11622351 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature