Severity of Airflow Obstruction Based on FEV₁/FVC Versus FEV₁ Percent Predicted in the General U.S. Population.

ABSTRACT: Rationale: According to the Global Initiative for Obstructive Lung Disease (GOLD), the FEV₁/FVC ratio is used to confirm the presence of airflow obstruction in the diagnosis of chronic obstructive pulmonary disease (COPD), whereas FEV₁ percent predicted normal value (FEV₁%pred) is used for grading its severity. The STaging of Airflow obstruction by the FEV₁/FVC Ratio (STAR), and its prediction of adverse outcomes, has not been evaluated in general populations. Objectives: To compare the STAR (FEV₁/FVC) and the GOLD (FEV₁%pred) classifications for the severity of airflow limitation in terms of exertional breathlessness and mortality in the general U.S. population. Methods: Severity stages according to the

SUBMITTER: Backman H 

PROVIDER: S-EPMC11622431 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature