Tracking myasthenia gravis severity over time: Insights from the French health insurance claims database.

ABSTRACT:

Background and purpose

Few data are available on the course of myasthenia gravis (MG) regarding disease severity and stability over time in real-world settings. This study used the French National Health Insurance Database (SNDS) to assess markers of disease severity in patients with MG longitudinally.

Methods

All patients with MG-related claims in the SNDS between 2013 and 2020 were identified. Patients were followed for up to 8 years after the first claim. Intensive care unit (ICU) stays, treatment with intravenous immunoglobulin (IVIg) or plasma exchange (PE), and death were documented throughout the follow-up period. Standardized mortality rates were estimated, and mortality-related variables were identified using a Cox model.

Results

In all, 14,459 individuals co

SUBMITTER: Attarian S 

PROVIDER: S-EPMC11622507 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature