Pneumococcal disease in children in the Middle East and Northern Africa: A systematic literature review of clinical burden, serotype distribution, and vaccination programs.

ABSTRACT: Bacterial diseases caused by S. pneumoniae are an important public health problem in Middle Eastern and North African countries. The burden of S. pneumoniae is poorly documented in these regions, local surveillance programs are lacking. This systematic review was conducted in Medline and Embase to obtain a comprehensive overview of the clinical burden of pneumococcal disease and pneumococcal vaccination status in the pediatric population in Middle East and Northern Africa. Overall, 255 articles and gray literature sources were included in the study, with the majority representing Israel (n = 82), Türkiye (n = 40), Iran (n = 27), and Saudi Arabia (n = 13). The incidence of pneumococcal disease varied based on time frame and country. The dominant IPD

SUBMITTER: Ugrekhelidze D 

PROVIDER: S-EPMC11622588 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature