Pregnancy outcomes in type 2 versus type 1 diabetes: systematic review with meta-analyses.

ABSTRACT:

Objective

Increasing numbers of pregnancies are complicated by pregestational diabetes mellitus, especially type 2 diabetes (T2DM). Some studies have reported similar or greater risks of adverse pregnancy outcomes among women with T2DM relative to type 1 diabetes (T1DM). We aimed to compare the risk of four pregnancy complications: pre-eclampsia, preterm delivery, macrosomia, and perinatal mortality, in pregnant women with T2DM vs T1DM in high-income countries.

Design

Systematic review with meta-analyses.

Methods

Systematic literature searches in Medline and Embase were performed. We included observational studies with original data of outcome occurrence in both women with pregestational T2DM and T1DM. Two researchers independently evaluated full-text studies for incl

SUBMITTER: Drablos M 

PROVIDER: S-EPMC11623030 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature