The role of the STING inflammatory pathway in hepatic damage in psoriasis with type 2 diabetes mellitus.

ABSTRACT:

Introduction

Studies have suggested a potential association between patients who have both psoriasis and diabetes and liver damage. However, the exact nature of this link has not yet been fully established. The objective of the current study was to examine the potential exacerbation of liver damage due to the coexistence of psoriasis and type 2 diabetes mellitus (T2DM) and to explore the impact of interferon gene stimulating factor (STING) on related damage.

Material and methods

Four patient groups were recruited: normal individuals, individuals with diabetes, those with psoriasis, and those with both diabetes and psoriasis. Relevant indicators were collected to facilitate the investigation. Furthermore, a mouse model of psoriasis combined with T2DM was established. The expr

SUBMITTER: Huang S 

PROVIDER: S-EPMC11623156 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature