CPLLM: Clinical prediction with large language models.

ABSTRACT: We present Clinical Prediction with Large Language Models (CPLLM), a method that involves fine-tuning a pre-trained Large Language Model (LLM) for predicting clinical disease and readmission. We utilized quantization and fine-tuned the LLM using prompts. For diagnostic predictions, we predicted whether patients would be diagnosed with a target disease during their next visit or in the subsequent diagnosis, leveraging their historical medical records. We compared our results to various baselines, including Retain and Med-BERT, the latter of which is the current state-of-the-art model for disease prediction using temporal structured EHR data. In addition, we also evaluated CPLLM's utility in predicting hospital readmission and compared our method's performance with benchmark baselines. Our e

SUBMITTER: Ben Shoham O 

PROVIDER: S-EPMC11623460 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature