Safety and efficacy of sertraline in depression among adults undergoing dialysis: a systematic review and meta-analysis.

ABSTRACT:

Background

Depression is prevalent among patients with end-stage renal disease (ESRD) undergoing dialysis, with significant implications for their quality of life and treatment compliance. Traditional treatments for depression, including various therapies and pharmacological interventions, have limitations due to their adverse effects. Sertraline, a selective serotonin re-uptake inhibitor (SSRI), offers a promising alternative, but its efficacy and safety in this population require thorough evaluation.

Objective

This meta-analysis aims to assess the effectiveness and adverse effects of sertraline in treating depressive episodes in dialysis patients compared to placebo.

Methods

Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) gu

SUBMITTER: Qammar A 

PROVIDER: S-EPMC11623899 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature