Hospital-Level Variation in COVID-19 Treatment Among Hospitalized Adults in the United States: A Retrospective Cohort Study.

ABSTRACT:

Study design

Retrospective cohort study.

Objective

To characterize variation in dexamethasone and remdesivir use over time among hospitals.

Background

Little is known about hospital-level variation in COVID-19 drug treatments in a large and diverse network in the United States.

Methods

We selected individuals hospitalized with COVID-19 across 163 hospitals between February 23, 2020 and October 31, 2021 from using the HCA CHARGE, an electronic health record repository from a network of community health care facilities in the United States. We quantified receipt of dexamethasone, remdesivir, and combined use of dexamethasone and remdesivir during the hospital stay. We used 2-level logistic regression models to determine the intraclass correlation coefficient (ICC

SUBMITTER: Alexander GC 

PROVIDER: S-EPMC11624058 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature