Proteinuria and albuminuria among a global primary cardiovascular disease prevention cohort of people with HIV.

ABSTRACT:

Objectives

To determine baseline prevalence of proteinuria and albuminuria among participants from the Randomized Trial to Prevent Vascular Events in HIV (REPRIEVE) and evaluate associated risk factors.

Design

Cross sectional analysis of a baseline sample of participants from the REPRIEVE Trial.

Methods

REPRIEVE is an international primary cardiovascular prevention randomized controlled trial (RCT) of pitavastatin calcium vs. placebo among people with HIV (PWH) on antiretroviral therapy (ART). A representative subset (2791 participants) had urine collected at study entry. Urine protein to creatinine ratios (uPCR) and albumin to creatinine ratios (uACR) were classified as normal, moderately increased and severely increased. These were dichotomized to Normal or Abnormal

SUBMITTER: Overton ET 

PROVIDER: S-EPMC11624062 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature