Hypertension control and risk of age-associated dementia in people with HIV infection.

ABSTRACT:

Objective

Hypertension is a major risk factor for dementia, but sustained blood pressure control is difficult to achieve. We evaluated whether inadequately controlled hypertension may contribute to excess dementia risk among people with HIV.

Design

A retrospective cohort study.

Methods

We studied demographically matched people with and without HIV between July 1, 2013, and December 31, 2021, who were at least 50 years old and had a hypertension diagnosis but no dementia diagnosis. Hypertension control was calculated using a disease management index (DMI), which captured degree and duration above the hypertension treatment goals of SBP less than 140 mmHg and DBP less than 90 mmHg. DMI values ranged from 0 to 100% (perfect control); hypertension was considered 'inadequa

SUBMITTER: Lam JO 

PROVIDER: S-EPMC11624069 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature