Association of cardiovascular disease risk with liver steatosis and fibrosis in people with HIV in low- and middle-income countries.

ABSTRACT:

Objective

The aim of this study was to understand the relationship between cardiovascular disease (CVD) risk and liver steatosis and fibrosis among people with HIV (PLWH) at least 40 years of age on antiretroviral therapy (ART) in low and middle-income countries (LMIC).

Design

We used cross-sectional behavioral and clinical data collected during study enrollment visits in 2020-2022 for the Sentinel Research Network of International epidemiology Databases to Evaluate AIDS (SRN of IeDEA).

Methods

Ten-year CVD risk was calculated using 2019 WHO nonlaboratory and laboratory models. Transient elastography was used to assess liver disease. Presence of steatosis and significant fibrosis were defined by controlled attenuation parameter (CAP) at least 248 dB/m and liver stiffn

SUBMITTER: Kuniholm MH 

PROVIDER: S-EPMC11624086 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature