Attenuated processing of vowels in the left temporal cortex predicts speech-in-noise perception deficit in children with autism.

ABSTRACT:

Background

Difficulties with speech-in-noise perception in autism spectrum disorders (ASD) may be associated with impaired analysis of speech sounds, such as vowels, which represent the fundamental phoneme constituents of human speech. Vowels elicit early (< 100 ms) sustained processing negativity (SPN) in the auditory cortex that reflects the detection of an acoustic pattern based on the presence of formant structure and/or periodic envelope information (f0) and its transformation into an auditory "object".

Methods

We used magnetoencephalography (MEG) and individual brain models to investigate whether SPN is altered in children with ASD and whether this deficit is associated with impairment in their ability to perceive speech in the background of noise. MEG was recorded whi

SUBMITTER: Fadeev KA 

PROVIDER: S-EPMC11624601 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature