Comparative adherence and persistence of single-inhaler and multiple-inhaler triple therapies among patients with chronic obstructive pulmonary disease in Japan: a retrospective cohort study.

ABSTRACT:

Objectives

To evaluate and compare medication adherence and persistence for patients newly initiating single-inhaler triple therapy (SITT) and multiple-inhaler triple therapy (MITT) for chronic obstructive pulmonary disease (COPD) in Japan.

Design

Retrospective, new-user, active comparator, observational cohort study using inverse probability of treatment weighting.

Setting

Health insurance claims data from the Medical Data Vision Co., Ltd, hospital claims database.

Participants

Adults diagnosed with COPD at age ≥40 years newly initiating MITT or SITT (fluticasone furoate/umeclidinium/vilanterol (FF/UMEC/VI) or formoterol fumarate/budesonide/glycopyrronium) from 1 September 2019 to 31 July 2021.

Primary and secondary outcome measures

The primary outcome

SUBMITTER: Joksaite S 

PROVIDER: S-EPMC11624741 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature