Prevalence and prognostic significance of pulmonary hypertension in adults with left ventricular diastolic dysfunction.

ABSTRACT:

Aims

Pulmonary hypertension (PHT) appears to be very common in heart failure with preserved ejection fraction but details on its prevalence, severity and prognostic implications have not been well defined. We, therefore, aimed to document PHT and its impact on mortality among adults with left ventricular (LV) diastolic dysfunction (LVDD).

Methods

We analysed the profile and outcomes of 16 058 adults with LVDD (and with preserved LV ejection fraction, >50%) from the National Echocardiography Database of Australia. Subjects were classified according to their peak tricuspid regurgitation velocity (TRV), reflecting PHT risk, and we then evaluated the relationship between conventional thresholds of increasing risk of PHT and subsequent mortality, during median follow-up of 3.1 (I

SUBMITTER: Ratwatte S 

PROVIDER: S-EPMC11624820 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature