Systematic review of prognostic models for predicting recurrence and survival in patients with treated oropharyngeal cancer.

ABSTRACT:

Objectives

This systematic review aims to evaluate externally validated models for individualised prediction of recurrence or survival in adults treated with curative intent for oropharyngeal cancer.

Design

Systematic review.

Setting

Hospital care.

Methods

Systematic searches were conducted up to September 2023 and records were screened independently by at least two reviewers. The Prediction model Risk Of Bias ASsessment Tool was used to assess risk of bias (RoB). Model discrimination measures (c-indices) were presented in forest plots. Clinical and methodological heterogeneity precluded meta-analysis.

Results

Fifteen studies developing and/or evaluating 25 individualised risk prediction models were included. The majority (77%) of c-indices for model dev

SUBMITTER: Dretzke J 

PROVIDER: S-EPMC11624838 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature