Cytokine Storm among Bangladeshi adults with COVID-19: A prospective cohort study.

ABSTRACT:

Objective

In COVID-19, cytokine storms (CS) result in higher mortality and morbidity. Our study evaluated the rate of cytokine storms among COVID-positive Bangladeshi adults.

Methods

From October 2020 to March 2022, this cohort study enrolled both COVID-positive and COVID-negative healthy adults. COVID-positive cases were treated in a makeshift COVID unit of icdr,b Dhaka Hospital. CS was defined as having IL-6 >80 pg/mL or any three of the following: high CRP, ferritin, LDH, D-dimer, or low lymphocyte. Stored plasma samples were tested for the cytokines IL-6, IL-1β, and TNF-α.

Results

This study involved 77 participants, 32 were in the severe-critical group, 30 were in the mild-moderate group, and 14 were COVID-negative. Twelve participants in the severe-critical grou

SUBMITTER: Sarmin M 

PROVIDER: S-EPMC11625268 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature