Regulatory effects of <i>Ishige okamurae</i> extract and Diphlorethohydroxycarmalol on skin barrier function.

ABSTRACT:

Ethnopharmacological relevance

The pharmacological potential of marine organisms remains largely unexplored. Ishige Okamurae, commonly known as Pae, is extensively distributed over Asia. Its antioxidant, antibacterial, antiobesity, and anti-inflammatory properties are also being investigated.

Aim of the study

In most cases of atopic dermatitis, the stratum corneum, the outermost layer of the epidermis, is damaged, causing symptoms such as dryness and hyperproliferation of the epidermis. In particular, the disruption of cell junctions leads to damage of the skin barrier, exacerbating the disease and becoming a target for therapeutic development. Our study aims to investigate of Ishige okamurae extract (IOE) and a major compound derived from it, called Diphlorethohydrox

SUBMITTER: Bak SG 

PROVIDER: S-EPMC11625274 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature