Transcriptomic data reveals MYC as an upstream regulator in laying hen follicular recruitment.

ABSTRACT: Understanding the mechanisms of follicular recruitment is essential for improving laying hen and broiler breeder productivity, as it directly influences egg production. Despite advancements in poultry breeding for enhanced egg production, the factors driving successful ovarian follicle maturation remain inadequately understood. This study investigates the genetic drivers mediating the transition of pre-recruitment follicles to the pre-ovulatory phase, a crucial stage before ovulation. Using RNA sequencing and bioinformatics approaches such as a differential gene expression analysis, we compared pre-recruitment follicles with the recently recruited F5 pre-ovulatory follicle to identify key genes and upstream regulators involved in this transition. Further validation through qRT-PCR confirme

SUBMITTER: Kramer AE 

PROVIDER: S-EPMC11625332 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature