Translocation of black carbon particles to human intestinal tissue.

ABSTRACT:

Background

Evidence is accumulating that elevated levels of particulate air pollution, including black carbon, have been linked to gastrointestinal disorders and a lower intestinal bacterial richness and diversity. One of the hypothesized underlying mechanisms is the absorption of air pollution-related particles from the gastrointestinal tract.

Methods

We visualized and quantified black carbon particles via white light generation under femtosecond-pulsed laser illumination in ileum and colon biopsies of five human patients. The biodistribution was assessed in three different layers (i.e., mucosa, submucosa, and muscularis propria).

Findings

Black carbon particles could be identified in all three tissue layers of the ileum and colon biopsies of five participants (two m

SUBMITTER: Van Pee T 

PROVIDER: S-EPMC11625357 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature