Development of cancer therapy-related cardiac dysfunction in anthracycline-treated breast cancer patients: a retrospective study.

ABSTRACT:

Purpose

Cardiac dysfunction as a result of anthracycline treatment is a major concern regarding the management of patient life after therapy. The aim of the present study was to determine the clinical characteristics of cancer patients at high risk of developing cancer therapy-related cardiac dysfunction (CTRCD), in order to improve the risk management for the appropriate treatment.

Methods

This is a single-center, retrospective study of patients with breast cancer who underwent anthracycline treatment and had regular consultations with cardiologists. To investigate the incidence of CTRCD and the risk factors related to its occurrence, left ventricular ejection fraction (LVEF), cardiac troponin I (TnI), and brain natriuretic peptide (BNP) were assessed in 177 patients at the

SUBMITTER: Kuroda J 

PROVIDER: S-EPMC11625689 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature