Association between tumor size and prognosis in bladder cancer: novel classifications and insights from a SEER database analysis.

ABSTRACT:

Objective

Although tumor size is an essential oncologic feature, it is often underutilized in diagnosing and treating bladder cancer (BC). This study investigates the relationship between tumor size and BC prognosis, aiming to enhance clinical applications.

Methods

BC patients were identified from the Surveillance, Epidemiology, and End Results (SEER) database (2004-2015). Cox proportional hazard models were conducted to identify prognostic factors, and restricted cubic splines (RCS) were used to assess the relationship between tumor size and survival outcomes. The Kaplan-Meier method and multivariate COX models were utilized to estimate the effect of the classification scheme.

Results

A total of 69,478 patients with BC were evaluated from the SEER database. Larger tu

SUBMITTER: Jia Y 

PROVIDER: S-EPMC11625752 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature