Operationalisation of post-COVID condition case definition in a comprehensive research protocol.

ABSTRACT:

Background and purpose

Post-COVID-19 condition (PCC) is a prevalent and high-burden sequela of SARS-CoV-2 infection. Because of the complexity of its manifestations, PCC case definition currently lacks standardisation and reproducibility. We aimed to devise a simple screening tool to boost reproducibility and comparability of PCC case definition across PCC studies, and to provide a framework in which to reliably identify suspected PCC cases. We also developed a comprehensive assessment protocol based on the most frequently reported PCC characteristics.

Methods

Within a European multi-centre study and based on the conclusions of a previous systematic review, we devised a checklist to assess the presence of PCC-associated symptoms and their temporal relationship with COVID-19.

SUBMITTER: Masserini F 

PROVIDER: S-EPMC11625920 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature