Associations of long-term nitrogen dioxide exposure with a wide spectrum of diseases: a prospective cohort study of 0·5 million Chinese adults.

ABSTRACT:

Background

Little evidence is available on the long-term health effects of nitrogen dioxide (NO₂) in low-income and middle-income populations. We investigated the associations of long-term NO₂ exposure with the incidence of a wide spectrum of disease outcomes, based on data from the China Kadoorie Biobank.

Methods

This prospective cohort study involved 512 724 Chinese adults aged 30-79 years recruited from ten areas of China during 2004-08. Time-varying Cox regression models yielded adjusted hazard ratios (HRs) for the associations of long-term NO₂ exposure with aggregated disease incidence endpoints classified by 14 ICD-10 chapters, and incidences of 12 specific diseases selected from three key ICD-10 chapters (cardiovascular, respiratory, a

SUBMITTER: Xia X 

PROVIDER: S-EPMC11626078 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature