Microbiome and Mycobiome Analyses of Continuous Positive Airway Pressure Devices.

ABSTRACT:

Objectives

Microorganisms are likely present in continuous positive airway pressure (CPAP) devices in daily use. Given the potential risk of infection among CPAP users, we aimed to compare the microbiomes of CPAP devices with those of nasal mucosa samples obtained from patients using these devices.

Methods

We conducted a prospective cohort study at multiple tertiary medical institutions. Samples were collected from the tubes and filters of CPAP devices and the nasal mucosa of device users. Microbiomes and mycobiomes were analyzed using 16S ribosomal RNA and internal transcribed spacer region sequencing. The results were compared according to sampling site and usage duration for each patient.

Results

Overall, 27 paired samples of human nasal mucosa and CPAP components

SUBMITTER: Min HJ 

PROVIDER: S-EPMC11626094 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature