Flexible bioelectronic systems with large-scale temperature sensor arrays for monitoring and treatments of localized wound inflammation.

ABSTRACT: Continuous monitoring and closed-loop therapy of soft wound tissues is of particular interest in biomedical research and clinical practices. An important focus is on the development of implantable bioelectronics that can measure time-dependent temperature distribution related to localized inflammation over large areas of wound and offer in situ treatment. Existing approaches such as thermometers/thermocouples provide limited spatial resolution, inapplicable to a wearable/implantable format. Here, we report a conformal, scalable device package that integrates a flexible amorphous silicon-based temperature sensor array and drug-loaded hydrogel for the healing process. This system can enable the spatial temperature mapping at submillimeter resolution and high sensitivity of 0.1 °C, for dynami

SUBMITTER: Liu J 

PROVIDER: S-EPMC11626133 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature