Transdermal characteristic study of bovine sialoglycoproteins with anti-skin aging and accelerating skin wound healing.

ABSTRACT:

Background

Sialoglycoproteins play important roles in various biological processes, including cell adhesion, immune response, and cell signaling. Our previous studies indicated that the bovine sialoglycoproteins could be developed as a reagent against skin aging and as a new candidate for accelerating skin wound healing as well as inhibiting scar formation. However, transdermal characteristic of the bovine sialoglycoproteins is still unknown.

Aims

This study investigated the transdermal permeation of the bovine sialoglycoproteins through porcine skin using the Franz diffusion cell method.

Results

Our study showed that the bovine sialoglycoproteins could penetrate through the porcine skin with a linear permeation pattern described by the regression equation N% = 11.49 

SUBMITTER: Cheng H 

PROVIDER: S-EPMC11626321 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature