Exploring the link between tooth loss, cognitive function, and brain wellness in the context of healthy aging.

ABSTRACT:

Aims

The aim of this study was to evaluate the utility of using MRI-derived tooth count, an indirect and nonspecific indicator of oral/periodontal health, and brain age gap (BAG), an MRI-based measure of premature brain aging, in predicting cognition in a population of otherwise healthy adults.

Methods

This retrospective study utilized data from 329 participants from the University of South Carolina's Aging Brain Cohort Repository. Participants underwent neuropsychological testing including the Montreal Cognitive Assessment (MoCA), completed an oral/periodontal health questionnaire, and submitted to high-resolution structural MRI imaging. The study compared variability on cognitive scores (MoCA) accounted for by MRI-derived BAG, MRI-derived total tooth count, and self-report

SUBMITTER: Newman-Norlund RD 

PROVIDER: S-EPMC11626696 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature